Science

How common is ain?

The incidence of AIN within the general population is difficult to estimate. Rates of anal cancer are low, with approximately 1.8 cases per 100,000 men and women.

Is Ain 2/3 a cancer?

AIN 2/3 are also known as high-grade dysplasia or high grade squamous intraepithelial lesions (HSIL). Some cases of AIN 2/3 may progress to anal cancer over time. There is no standard for how to treat AIN. Some cases will regress, if left untreated, however it is difficult to predict which ones will do this.

Can Ain be cured?

AIN can be treated using topical therapies such as imiquimod, 5-flurouracil, and trichloroacetic acid, as well as ablative therapies such as electrocautery and laser therapy.

What does Ain look like?

Doctors describe AIN as either low grade or high grade, depending on how the cells look under the microscope. Low-grade AIN cells look much like normal cells and will often return to normal on their own. High-grade AIN cells look very abnormal under the microscope and usually don't return to normal.

How is Ain treated?

Topical treatments such as Imiquimod, Cidofovir and 5-Fluorouracil and ablative treatments such as electrocautery, laser therapy and radiofrequency ablation can all be used to treat AIN. People diagnosed with HPV associated AIN may also be considered for vaccination against multiple strains of HPV.

Does Ain 3 go away?

AIN2 and AIN3 are also known as ‘moderate to severe dysplasia’, or HSIL which means ‘high-grade squamous intraepithelial lesion’. Most cases of AIN2 and AIN3 stay the way they are (sometimes for decades) or go away on their own.

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