Science

What is it Tai Tai disease?

Itai-itai disease (イタイイタイ病, itai-itai byō, “it hurts-it hurts disease”) was the name given to the mass cadmium poisoning of Toyama Prefecture, Japan, starting around 1912. The term “itai-itai disease” was coined by locals for the severe pains (Japanese: 痛い itai) people with the condition felt in the spine and joints.

What is cause of Itai disease?

Itai-itai disease is caused by cadmium (Cd) exposure, produced as a result of human activities related to industrialisation, and this condition was first recognised in Japan in the 1960s. Itai-itai disease is characterised by osteomalaecia with severe bone pain and is associated with renal tubular dysfunction.

What is the meaning of Itai-Itai?

Medical Definition of itai-itai

: an extremely painful condition caused by poisoning following the ingestion of cadmium and characterized by bone decalcification. — called also itai-itai disease.

What is ouch ouch disease?

Itai-Itai ByŌ, the literal translation of which is "ouch-ouch" disease, is derived from the typical cry of patients with extreme bone pain due to osteomalacia, who are commonly seen in Toyama city on Japan's Inland Sea.

Which metal is responsible for itai-itai disease?

Abstract. Cadmium (Cd) is one of the most toxic elements to which humans could be exposed at work or in the environment. The outbreak of itai-itai disease, which is the most severe stage of chronic Cd poisoning, occurred in the Cd-polluted Jinzu River basin in Toyama.

What is it Tai Tai disease?

Itai-itai disease is the most severe form of chronic Cd poisoning caused by prolonged oral Cd ingestion. It developed in numerous inhabitants of the Jinzu River basin in Toyama Prefecture, Japan, an area most severely polluted by Cd that originated from a zinc mine located upstream.

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Which metal is responsible for disease?

The heavy metals most commonly associated with poisoning of humans are lead, mercury, arsenic and cadmium. Heavy metal poisoning may occur as a result of industrial exposure, air or water pollution, foods, medicines, improperly coated food containers, or the ingestion of lead-based paints.

What Itai mean in Japanese?

痛い (itai): Simple. When it’s found in a full sentence, it means “painful” or something “hurts” or is “sore.” No room for discussion. But there is one major situation where the translation strays.

What is Itai-Itai?

Itai-itai disease is caused by cadmium (Cd) exposure, produced as a result of human activities related to industrialisation, and this condition was first recognised in Japan in the 1960s. 1 2. Itai-itai disease is characterised by osteomalaecia with severe bone pain and is associated with renal tubular dysfunction.

What is a tie a tie disease?

Tongue-tie (ankyloglossia) is a condition in which an unusually short, thick or tight band of tissue (lingual frenulum) tethers the bottom of the tongue’s tip to the floor of the mouth. If necessary, tongue-tie can be treated with a surgical cut to release the frenulum (frenotomy).

Which is a primary source of food contamination by cadmium in Japan?

Because the staple food in Japan is rice, which absorbs cadmium (Cd) from the soil efficiently, rice is the main source of exposure to Cd in the Japanese population. In addition, there have been many Cd-contaminated farming areas in Japan.

How toxic is gold?

In its metallic form, gold is not toxic, which is why we can eat ice cream with gold flakes. However, some natural gold compounds will break down in the body releasing gold ions, which can have toxic effects on living organisms. The same goes for copper, but bacteria has another way to get rid of extra copper.

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What is black foot disease?

Blackfoot disease is a characteristic vascular disease associated with long-term exposure to inorganic arsenic. It occurred in areas of Taiwan with elevated arsenic in drinking water. The patients suffer severe systemic arteriosclerosis with black, mummified dry foot-gangrene in severe cases.

How do Japanese express pain?

Pain in English has the meaning of punishment in the verbal origin. However, pain in Japanese, which is called “itami”, means extraordinary state of something without containing the meaning of punishment.

What is Kore wa?

kore – これ : a demonstrative pronoun used to refer to something close to the speaker. This is often translated into English as “this”. wa – は : a binding particle working as a case marker or topic marker. In the phrase, this works after “kore” to make the subject word.

What makes cadmium toxic?

Cadmium causes mutations and chromosomal deletions potentially (17). Its toxicity involves depletion of reduced glutathione (GSH), binds sulfhydryl groups with protein, and causes to enhance production of reactive oxygen species (ROS) such as superoxide ion, hydrogen peroxide, and hydroxyl radicals.

Why are CDS toxic?

Cadmium causes mutations and chromosomal deletions potentially (17). Its toxicity involves depletion of reduced glutathione (GSH), binds sulfhydryl groups with protein, and causes to enhance production of reactive oxygen species (ROS) such as superoxide ion, hydrogen peroxide, and hydroxyl radicals.

Does coffee have cadmium?

Apart from antioxidants and other bioactive compounds, coffee contains carbohydrates, lipids, nitrogen compounds, vitamins and minerals, including toxic elements such as cadmium (Cd) and lead (Pb) [12, 14, 15].

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